Top ▲

carboxylesterase 1

Click here for help

Target not currently curated in GtoImmuPdb

Target id: 2592

Nomenclature: carboxylesterase 1

Abbreviated Name: CES1

Family: Hydrolases

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 567 16q12.2 CES1 carboxylesterase 1
Mouse - 565 8 45.29 cM Ces1g carboxylesterase 1G
Rat - 565 19p11 Ces1d carboxylesterase 1D
Previous and Unofficial Names Click here for help
CEH | HMSE1 | monocyte/macrophage serine esterase 1 | SES1
Database Links Click here for help
Specialist databases
MEROPS S09.982 (Hs)
Other databases
BRENDA
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 3.1.1.1

Download all structure-activity data for this target as a CSV file go icon to follow link

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
GR148672X Small molecule or natural product Hs Inhibition 8.4 pIC50 1
pIC50 8.4 (IC50 4x10-9 M) [1]

References

Show »

1. Borg-Capra Catherine Sylvia et al.. (2001) Method of screening for triacyglycerol hydrolase inhibitors. Patent number: WO2001016358. Assignee: Glaxo (now GSK). Priority date: 23/08/1999. Publication date: 08/03/2001.

How to cite this page