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Target not currently curated in GtoImmuPdb
Target id: 2592
Nomenclature: carboxylesterase 1
Abbreviated Name: CES1
Family: Hydrolases & Lipases
Gene and Protein Information  |
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| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | - | 567 | 16q12.2 | CES1 | carboxylesterase 1 | |
| Mouse | - | 565 | 8 45.29 cM | Ces1g | carboxylesterase 1G | |
| Rat | - | 565 | 19p11 | Ces1d | carboxylesterase 1D | |
| Previous and Unofficial Names |
| CEH | HMSE1 | monocyte/macrophage serine esterase 1 | SES1 |
| Database Links |
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| Specialist databases | |
| MEROPS | S09.982 (Hs) |
| Other databases | |
| Alphafold | P23141 (Hs), Q8VCC2 (Mm), P16303 (Rn) |
| BRENDA | 3.1.1.1 |
| CATH/Gene3D | 3.40.50.1820 |
| ChEMBL Target | CHEMBL2265 (Hs), CHEMBL4105953 (Mm) |
| DrugBank Target | P23141 (Hs) |
| Ensembl Gene | ENSG00000198848 (Hs), ENSMUSG00000057074 (Mm), ENSRNOG00000015438 (Rn), ENSRNOG00000015519 (Rn) |
| Entrez Gene | 1066 (Hs), 12623 (Mm), 113902 (Rn) |
| Human Protein Atlas | ENSG00000198848 (Hs) |
| KEGG Enzyme | 3.1.1.1 |
| KEGG Gene | hsa:1066 (Hs), mmu:12623 (Mm), rno:113902 (Rn) |
| OMIM | 605278 (Hs) |
| Pharos | P23141 (Hs) |
| RefSeq Nucleotide | NM_001025194 (Hs), NM_021456 (Mm), NM_133295 (Rn) |
| RefSeq Protein | NP_001020365 (Hs), NP_067431 (Mm), NP_579829 (Rn) |
| UniProtKB | P23141 (Hs), Q8VCC2 (Mm), P16303 (Rn) |
| Wikipedia | CES1 (Hs) |
| Enzyme Reaction |
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Download all structure-activity data for this target as a CSV file 
| Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||
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1. Borg-Capra Catherine Sylvia et al.. (2001) Method of screening for triacyglycerol hydrolase inhibitors. Patent number: WO2001016358. Assignee: Glaxo (now GSK). Priority date: 23/08/1999. Publication date: 08/03/2001.
