amylase alpha 2A | 3.2.1.- Glycosidases | IUPHAR/BPS Guide to PHARMACOLOGY

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amylase alpha 2A

Target not currently curated in GtoImmuPdb

Target id: 2596

Nomenclature: amylase alpha 2A

Family: 3.2.1.- Glycosidases

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 511 1p21.1 AMY2A amylase alpha 2A
Mouse - 508 3 F3 Amy2a5 amylase 2a5
Rat - 508 2q41 Amy2a3 amylase 2a3
Previous and Unofficial Names
amylase alpha 2A (pancreatic) | amylase, alpha 2A (pancreatic) | pancreatic alpha-amylase
Database Links
BRENDA
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.2.1.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
acarbose Pig Inhibition 4.4 pIC50 1
pIC50 4.4 (IC50 3.55x10-5 M) [1]

References

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1. Patil VS, Nandre KP, Ghosh S, Rao VJ, Chopade BA, Bhosale SV, Bhosale SV. (2012) Synthesis and glycosidase inhibitory activity of novel (2-phenyl-4H-benzopyrimedo[2,1-b]-thiazol-4-yliden)acetonitrile derivatives. Bioorg. Med. Chem. Lett., 22 (23): 7011-4. [PMID:23102653]

How to cite this page

3.2.1.- Glycosidases: amylase alpha 2A. Last modified on 12/09/2019. Accessed on 29/02/2020. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2596.