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bromodomain PHD finger transcription factor

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Target not currently curated in GtoImmuPdb

Target id: 2723

Nomenclature: bromodomain PHD finger transcription factor

Family: Non-enzymatic BRD containing proteins

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 3046 17q24.2 BPTF bromodomain PHD finger transcription factor
Mouse - 2921 11 E1 Bptf bromodomain PHD finger transcription factor
Rat - - 10q32.1 Bptf bromodomain PHD finger transcription factor
Previous and Unofficial Names Click here for help
FAC1 | FALZ
Database Links Click here for help
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

Download all structure-activity data for this target as a CSV file go icon to follow link

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
MS363 Small molecule or natural product Click here for species-specific activity table Hs Inhibition 5.8 pKi 1
pKi 5.8 (Ki 1.62x10-6 M) [1]

References

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1. Zhang G, Plotnikov AN, Rusinova E, Shen T, Morohashi K, Joshua J, Zeng L, Mujtaba S, Ohlmeyer M, Zhou MM. (2013) Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains. J. Med. Chem., 56 (22): 9251-64. [PMID:24144283]

How to cite this page

Non-enzymatic BRD containing proteins: bromodomain PHD finger transcription factor. Last modified on 13/02/2017. Accessed on 04/12/2020. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2723.