bromodomain containing 1 | Bromodomain kinase (BRDK) family | IUPHAR/BPS Guide to PHARMACOLOGY

Top ▲

bromodomain containing 1

Target not currently curated in GtoImmuPdb

Target id: 2724

Nomenclature: bromodomain containing 1

Abbreviated Name: BRD1

Family: Bromodomain kinase (BRDK) family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 1058 22q13.33 BRD1 bromodomain containing 1
Mouse - 1189 15 E3 Brd1 bromodomain containing 1
Rat - 1058 7q34 Brd1 bromodomain containing 1
Previous and Unofficial Names
BRPF2
Database Links
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
NI-57 Hs Binding 7.0 pKd 2
pKd 7.0 (Kd 1.08x10-7 M) [2]
BAY-299 Hs Inhibition 8.2 pIC50 1
pIC50 8.2 (IC50 6x10-9 M) [1]
Description: In a BROMOscan® assay.

References

Show »

1. SGC. BAY-299 A probe for BRD1 and TAF1. Accessed on 05/04/2017. Modified on 05/04/2017. SGC, http://www.thesgc.org/chemical-probes/BAY-299

2. Structural Genomics Consortium. NI-57 – a chemical probe for BRPF bromodomains. Accessed on 15/07/2015. Modified on 15/07/2015. http://www.thesgc.org, http://www.thesgc.org/chemical-probes/NI-57

How to cite this page

Bromodomain kinase (BRDK) family: bromodomain containing 1. Last modified on 05/04/2017. Accessed on 28/01/2020. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2724.