Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	517	4q12	PPAT	phosphoribosyl pyrophosphate amidotransferase
Mouse	-	517	5 C3	Ppat	phosphoribosyl pyrophosphate amidotransferase
Rat	-	517	14p11	Ppat	phosphoribosyl pyrophosphate amidotransferase

Previous and Unofficial Names

PRAT | glutamine phosphoribosylpyrophosphate amidotransferase | GPAT | amidophosphoribosyltransferase

Database Links
Specialist databases
MEROPS	C44.001 (Hs)
Other databases
Alphafold	Q06203 (Hs), P35433 (Rn)
BRENDA	2.4.2.14
CATH/Gene3D	3.60.20.10
ChEMBL Target	CHEMBL2362992 (Hs)
Ensembl Gene	ENSG00000128059 (Hs), ENSMUSG00000029246 (Mm), ENSRNOG00000002128 (Rn)
Entrez Gene	5471 (Hs), 231327 (Mm), 117544 (Rn)
Human Protein Atlas	ENSG00000128059 (Hs)
KEGG Enzyme	2.4.2.14
KEGG Gene	hsa:5471 (Hs), mmu:231327 (Mm), rno:117544 (Rn)
OMIM	172450 (Hs)
Pharos	Q06203 (Hs)
RefSeq Nucleotide	NM_002703 (Hs), NM_172146 (Mm), NM_057198 (Rn)
RefSeq Protein	NP_002694 (Hs), NP_742158 (Mm), NP_476546 (Rn)
UniProtKB	Q06203 (Hs), P35433 (Rn)
Wikipedia	PPAT (Hs)

Enzyme Reaction
EC Number: 2.4.2.14

General Comments
Confirmed enzymatic activity of PPAT is primarily as a glutamine amidotransferase. InterPro does not predict protease domain matches but does identify protease-like fold structure (see also the MEROPS cross-link in the Database Links table above).