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acyloxyacyl hydrolase

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Target not currently curated in GtoImmuPdb

Target id: 2873

Nomenclature: acyloxyacyl hydrolase

Family: 3.1.1.- Carboxylic Ester Hydrolases

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 575 7p14.2 AOAH acyloxyacyl hydrolase
Mouse - 574 13 A2 Aoah acyloxyacyl hydrolase
Rat - 574 17q11 Aoah acyloxyacyl hydrolase
Previous and Unofficial Names Click here for help
acyloxyacyl hydrolase (neutrophil)
Database Links Click here for help
Alphafold
BRENDA
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 3.1.1.77

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
JZL195 Small molecule or natural product Click here for species-specific activity table Hs Inhibition 7.4 pIC50 1
pIC50 7.4 (IC50 4.4x10-8 M) [1]
Immuno Process Associations
Immuno Process:  Immune regulation
Immuno Process:  Inflammation

References

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1. Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE et al.. (2014) A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat Chem Biol, 10 (8): 656-63. [PMID:24997602]

How to cite this page

3.1.1.- Carboxylic Ester Hydrolases: acyloxyacyl hydrolase. Last modified on 29/01/2016. Accessed on 18/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2873.