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protein phosphatase methylesterase 1

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Target not currently curated in GtoImmuPdb

Target id: 2875

Nomenclature: protein phosphatase methylesterase 1

Family: 3.1.1.- Carboxylic Ester Hydrolases, S33: Prolyl aminopeptidase

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 386 11q13.4 PPME1 protein phosphatase methylesterase 1
Mouse - 386 7 E2 Ppme1 protein phosphatase methylesterase 1
Rat - 386 1q32 Ppme1 protein phosphatase methylesterase 1
Previous and Unofficial Names Click here for help
PME-1 | PME1
Database Links Click here for help
BRENDA
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 3.1.1.89

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
ABL127 Small molecule or natural product Hs Inhibition 7.9 pIC50 1
pIC50 7.9 (IC50 1.2x10-8 M) [1]

References

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1. Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE et al.. (2014) A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat. Chem. Biol., 10 (8): 656-63. [PMID:24997602]

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