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protein phosphatase methylesterase 1

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Target not currently curated in GtoImmuPdb

Target id: 2875

Nomenclature: protein phosphatase methylesterase 1

Family: 3.1.1.- Carboxylic Ester Hydrolases, S33: Prolyl aminopeptidase

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 386 11q13.4 PPME1 protein phosphatase methylesterase 1
Mouse - 386 7 E2 Ppme1 protein phosphatase methylesterase 1
Rat - 386 1q32 Ppme1 protein phosphatase methylesterase 1
Previous and Unofficial Names Click here for help
PME-1 | PME1
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:

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Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
ABL127 Small molecule or natural product Hs Inhibition 7.9 pIC50 1
pIC50 7.9 (IC50 1.2x10-8 M) [1]


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1. Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE et al.. (2014) A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat Chem Biol, 10 (8): 656-63. [PMID:24997602]

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