Top ▲

cryptochrome circadian regulator 1

Click here for help

Target not currently curated in GtoImmuPdb

Target id: 2876

Nomenclature: cryptochrome circadian regulator 1

Family: Circadian clock proteins

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 586 12q23.3 CRY1 cryptochrome circadian regulator 1
Mouse - 606 10 41.63 cM Cry1 cryptochrome 1 (photolyase-like)
Rat - 588 7q13 Cry1 cryptochrome circadian regulator 1
Previous and Unofficial Names Click here for help
cryptochrome 1 (photolyase-like) | cryptochrome circadian clock 1 | PHLL1
Database Links Click here for help
Alphafold
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Other Binding Ligands
Key to terms and symbols Click column headers to sort
Ligand Sp. Action Value Parameter Reference
KL044 Small molecule or natural product Primary target of this compound Ligand has a PDB structure Hs Binding 7.2 pEC50 1
pEC50 7.2 (EC50 6.3x10-8 M) [1]
Immuno Process Associations
Immuno Process:  Cellular signalling
GO Annotations:  Associated to 2 GO processes
GO:0031397 negative regulation of protein ubiquitination ISS
GO:0031398 positive regulation of protein ubiquitination ISS

References

Show »

1. Lee JW, Hirota T, Kumar A, Kim NJ, Irle S, Kay SA. (2015) Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock. ChemMedChem, 10 (9): 1489-97. [PMID:26174033]

How to cite this page

Circadian clock proteins: cryptochrome circadian regulator 1. Last modified on 15/02/2021. Accessed on 01/12/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2876.