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target has curated data in GtoImmuPdb
Target id: 3142
Nomenclature: T-cell surface glycoprotein CD3 zeta chain (CD247)
Family: CD molecules
Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 1 | 164 | 1q24.2 | CD247 | CD247 molecule | |
Mouse | 1 | 164 | 1 73.14 cM | Cd247 | CD247 antigen | |
Rat | 1 | 164 | 13q23 | Cd247 | Cd247 molecule |
Database Links ![]() |
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Alphafold | P20963 (Hs), P24161 (Mm), Q4V7G0 (Rn) |
Ensembl Gene | ENSG00000198821 (Hs), ENSMUSG00000005763 (Mm), ENSRNOG00000003298 (Rn) |
Entrez Gene | 919 (Hs), 12503 (Mm), 25300 (Rn) |
Human Protein Atlas | ENSG00000198821 (Hs) |
KEGG Gene | hsa:919 (Hs), mmu:12503 (Mm), rno:25300 (Rn) |
Pharos | P20963 (Hs) |
UniProtKB | P20963 (Hs), P24161 (Mm), Q4V7G0 (Rn) |
Wikipedia | CD247 (Hs) |
Immunopharmacology Comments |
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. |
CD molecules: T-cell surface glycoprotein CD3 zeta chain (CD247). Last modified on 30/07/2020. Accessed on 19/02/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=3142.