Adipo2 receptor | Adiponectin receptors | IUPHAR/BPS Guide to PHARMACOLOGY

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Adipo2 receptor

Target not currently curated in GtoImmuPdb

Target id: 650

Nomenclature: Adipo2 receptor

Family: Adiponectin receptors

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 386 12p13 ADIPOR2 adiponectin receptor 2
Mouse 7 386 6 6 60.7 Adipor2 adiponectin receptor 2
Rat - - 4q42 Adipor2 adiponectin receptor 2
Previous and Unofficial Names
ACDCR2 | PAQR2 | adiponectin receptor 2 | progestin and adipoQ receptor family member II
Database Links
ChEMBL Target
Ensembl Gene
Human Protein Atlas
Selected 3D Structures
Image of receptor 3D structure from RCSB PDB
Description:  Crystal structure of the human adiponectin receptor 2
Resolution:  2.4Å
Species:  Human
References:  1
Natural/Endogenous Ligands
adiponectin {Sp: Human}
globular adiponectin {Sp: Human}
Rank order of potency (Human)
globular adiponectin (ADIPOQ, Q15848) = adiponectin (ADIPOQ, Q15848)
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 1 GO processes
GO:0033211 adiponectin-activated signaling pathway IDA


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1. Tanabe H, Fujii Y, Okada-Iwabu M, Iwabu M, Nakamura Y, Hosaka T, Motoyama K, Ikeda M, Wakiyama M, Terada T et al.. (2015) Crystal structures of the human adiponectin receptors. Nature, 520 (7547): 312-6. [PMID:25855295]

How to cite this page

Adiponectin receptors: Adipo2 receptor. Last modified on 27/04/2015. Accessed on 01/10/2020. IUPHAR/BPS Guide to PHARMACOLOGY,