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target has curated data in GtoImmuPdb
Target id: 770
Nomenclature: ABCB3
Abbreviated Name: TAP2
Systematic Nomenclature: ABCB3
Family: ABCB subfamily
Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 9 | 686 | 6p21.32 | TAP2 | transporter 2, ATP binding cassette subfamily B member | |
Mouse | 9 | 702 | 17 17.98 cM | Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | |
Rat | 9 | 703 | 20p12 | Tap2 | transporter 2, ATP binding cassette subfamily B member |
Database Links | |
Alphafold | Q03519 (Hs), P36371 (Mm), P36372 (Rn) |
ChEMBL Target | CHEMBL4523654 (Hs) |
Ensembl Gene | ENSG00000204267 (Hs), ENSMUSG00000024339 (Mm), ENSRNOG00000000455 (Rn) |
Entrez Gene | 6891 (Hs), 21355 (Mm), 24812 (Rn) |
Human Protein Atlas | ENSG00000204267 (Hs) |
KEGG Gene | hsa:6891 (Hs), mmu:21355 (Mm), rno:24812 (Rn) |
OMIM | 170261 (Hs) |
Pharos | Q03519 (Hs) |
UniProtKB | Q03519 (Hs), P36371 (Mm), P36372 (Rn) |
Wikipedia | TAP2 (Hs) |
Immunopharmacology Comments |
TAP1 (ABCB2) and TAP2 (ABCB3) form a transporter that plays an important role in antigen presentation by major histocompatibility complex class I (MHCI) molecules in the adaptive immune response [1]. |
Immuno Process Associations | ||
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