Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	9	686	6p21.32	TAP2	transporter 2, ATP binding cassette subfamily B member
Mouse	9	702	17 17.98 cM	Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Rat	9	703	20p12	Tap2	transporter 2

Previous and Unofficial Names

Antigen peptide transporter 2 (APT2) | peptide supply factor 2 (PSF-2) | Peptide transporter TAP2 | ATP-binding cassette sub-family B member 3 | Cim | Transporter 2 ABC (ATP binding cassette) | Ham2 | MTP2 | peptide transporter involved in antigen processing 2 | RING11 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | transporter 2 | transporter 2, ATP binding cassette subfamily B member

Database Links
Alphafold	Q03519 (Hs), P36371 (Mm), P36372 (Rn)
ChEMBL Target	CHEMBL4523654 (Hs)
Ensembl Gene	ENSG00000204267 (Hs), ENSMUSG00000024339 (Mm), ENSRNOG00000000455 (Rn)
Entrez Gene	6891 (Hs), 21355 (Mm), 24812 (Rn)
Human Protein Atlas	ENSG00000204267 (Hs)
KEGG Gene	hsa:6891 (Hs), mmu:21355 (Mm), rno:24812 (Rn)
OMIM	170261 (Hs)
Pharos	Q03519 (Hs)
UniProtKB	Q03519 (Hs), P36371 (Mm), P36372 (Rn)
Wikipedia	TAP2 (Hs)

Immunopharmacology Comments

TAP1 (ABCB2) and TAP2 (ABCB3) form a transporter that plays an important role in antigen presentation by major histocompatibility complex class I (MHCI) molecules in the adaptive immune response [1].

Immuno Process Associations

Immuno Process:  Antigen presentation GO Annotations:  Associated to 5 GO processes GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent IMP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IDA GO:0046968 peptide antigen transport IDA click arrow to show/hide IEA associations GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent IEA GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent IEA

Immuno Process:  T cell (activation) GO Annotations:  Associated to 2 GO processes, IEA only click arrow to show/hide IEA associations GO:0001913 T cell mediated cytotoxicity IEA GO:0001916 positive regulation of T cell mediated cytotoxicity IEA

Immuno Process:  B cell (activation) GO Annotations:  Associated to 2 GO processes, IEA only click arrow to show/hide IEA associations GO:0001913 T cell mediated cytotoxicity IEA GO:0001916 positive regulation of T cell mediated cytotoxicity IEA

Immuno Process:  Immune regulation GO Annotations:  Associated to 1 GO processes click arrow to show/hide IEA associations GO:0001916 positive regulation of T cell mediated cytotoxicity IEA

Immuno Process:  Inflammation