Top ▲

GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

Search results

Your search for Remdesivir returned 10 results

Order results by:
Download as a CSV:
Disease: Alzheimer disease
Disease Name: Alzheimer disease
Disease Synonym: Alzheimer's disease
Pathophysiology comments: Alzheimer's disease. Inhbition of C5aR, through oral administration of PMX205, in these models reduces
Pathophysiology role: Alzheimer's disease anti-PD1 antibody treatment was used to induce immune checkpoint blockade. The biological
Pathophysiology role: neurons and may be a potential therapeutic target for the treatment of Alzheimer's disease
Disease: Alzheimer disease 4
Disease Name: Alzheimer disease 4
Disease Synonym: Early-onset autosomal dominant Alzheimer disease
Disease Synonym: Alzheimer's disease
Disease: Alzheimer disease 3
Disease Name: Alzheimer disease 3
Disease Synonym: Early-onset autosomal dominant Alzheimer disease
Disease Synonym: Alzheimer's disease
Disease: Major affective disorder 2; MAFD2
Pathophysiology comments: role for GPR50 in mental disorders, such as Alzheimer's and schizophrenia, has been postulated .
Target: dihydroorotate dehydrogenase (quinone) (Nucleoside synthesis and metabolism, 1.-.-.- Oxidoreductases)
Comment: remdesivir) have demonstrated synergistic/additive antiviral activity in mice . PTC Therapeutics are taking their DHODH inhibitor
Target: CoV RNA-dependent RNA polymerase (Coronavirus (CoV) proteins)
Comment: remdesivir. Although RdRp (nsp12) is strictly a component of the SARS-CoV-2 replicase polyprotein
Target: CoV Replicase polyprotein 1ab (Coronavirus (CoV) proteins)
Comment: remdesivir, tenofovir and ribavirin . It has a zinc-binding domain in its N-terminus and its activity
Target: CoV Papain-like protease (Coronavirus (CoV) proteins)
Comment: remdesivir. The search for novel, selective PLpro inhibitors has revealed compounds such as GRL-0617 and compound
Target: programmed cell death 1 (CD279) (Other immune checkpoint proteins, CD molecules)
Receptor Immuno Comment: Alzheimer's disease (AD): In mouse models of AD anti-PD-1 antibody treatment was used
Target: advanced glycosylation end-product specific receptor (Immunoglobulin like domain containing proteins)
Receptor Immuno Comment: industry, for the development of novel therapies for conditions including diabetes mellitus and Alzheimer's disease (AD) .

1

Target search page
Ligand search page
Pharmacology search page