Disease Name: Alzheimer disease Disease Synonym: Alzheimer's disease Pathophysiology comments: Alzheimer's disease. Inhbition of C5aR, through oral administration of PMX205, in these models reduces Pathophysiology role: Alzheimer's disease anti-PD1 antibody treatment was used to induce immune checkpoint blockade. The biological Pathophysiology role: neurons and may be a potential therapeutic target for the treatment of Alzheimer's disease