Sialic acid binding Ig like lectins

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Sialic acid binding Ig like lectins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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SIGLECs are a family of type I transmembrane proteins that are predominantly expressed by hemopoietic cells.

Targets

SIGLEC-2 (CD22) Show summary »« Hide summary More detailed page

Target Id	2786
Nomenclature	CD22
Common abbreviation	SIGLEC-2
Previous and unofficial names	sialic acid binding Ig-like lectin 2 \| SIGLEC-2 \| B-lymphocyte cell adhesion molecule
Genes	CD22 (Hs)
Ensembl ID	ENSG00000012124 (Hs)
UniProtKB AC	P20273 (Hs)

SIGLEC-3 (CD33) C Show summary »« Hide summary More detailed page

SIGLEC8 (sialic acid binding Ig like lectin 8) Show summary »« Hide summary More detailed page

Target Id	3012
Nomenclature	sialic acid binding Ig like lectin 8
Common abbreviation	SIGLEC8
Previous and unofficial names	SAF2 \| SIGLEC-8 \| SIGLEC8L
Genes	SIGLEC8 (Hs), Siglecf (Mm), Siglec8 (Rn)
Ensembl ID	ENSG00000105366 (Hs), ENSMUSG00000039013 (Mm)
UniProtKB AC	Q9NYZ4 (Hs), Q920G3 (Mm)

References

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How to cite this family page

Database page citation:

Sialic acid binding Ig like lectins. Accessed on 23/02/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1000.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Overview. Br J Pharmacol. 174 Suppl 1: S1-S16.