Top ▲

Aminoacyl-tRNA synthetases

Overview

Click here for help

« Hide

The aminoacyl-tRNA synthetases (aaRSs) are emerging targets for antimalarial agents [2]. Although sharing a common tRNA esterification catalytic activity, these proteins are structurally diverse and physiologically distinct enzymes [1].

Targets

Click here for help

PfaIRS (Plasmodium falciparum isoleucine--tRNA ligase) C Show summary » More detailed page go icon to follow link

PfcKRS (Plasmodium falciparum lysine--tRNA ligase) C Show summary » More detailed page go icon to follow link

PfcFRS (Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit) C Show summary » More detailed page go icon to follow link

PfcPRS (Plasmodium falciparum proline--tRNA ligase) C Show summary » More detailed page go icon to follow link

PfTRS (Plasmodium falciparum threonine--tRNA ligase) C Show summary » More detailed page go icon to follow link

PfaWRS (Plasmodium falciparum tryptophan--tRNA ligase) C Show summary » More detailed page go icon to follow link

References

Click here for help

Show »

How to cite this family page

Database page citation:

Aminoacyl-tRNA synthetases. Accessed on 23/01/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1050.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Introduction and Other Protein Targets. Br J Pharmacol. 176 Issue S1: S1-S20.