Along with the SLC4 family, the SLC26 family acts to allow movement of monovalent and divalent anions across cell membranes. The predicted topology is of 10-14 TM domains with intracellular C- and N-termini, probably existing as dimers. Within the family, subgroups may be identified on the basis of functional differences, which appear to function as anion exchangers and anion channels (SLC26A7 and SLC26A9).

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* Key recommended reading is highlighted with an asterisk

* Alper SL, Sharma AK. (2013) The SLC26 gene family of anion transporters and channels. Mol Aspects Med, 34 (2-3): 494-515. [PMID:23506885]

Dorwart MR, Shcheynikov N, Yang D, Muallem S. (2008) The solute carrier 26 family of proteins in epithelial ion transport. Physiology (Bethesda), 23: 104-14. [PMID:18400693]

* Kato A, Romero MF. (2011) Regulation of electroneutral NaCl absorption by the small intestine. Annu Rev Physiol, 73: 261-81. [PMID:21054167]

Mount DB, Romero MF. (2004) The SLC26 gene family of multifunctional anion exchangers. Pflugers Arch, 447 (5): 710-21. [PMID:12759755]

* Nofziger C, Dossena S, Suzuki S, Izuhara K, Paulmichl M. (2011) Pendrin function in airway epithelia. Cell Physiol Biochem, 28 (3): 571-8. [PMID:22116372]

Ohana E, Yang D, Shcheynikov N, Muallem S. (2009) Diverse transport modes by the solute carrier 26 family of anion transporters. J Physiol (Lond.), 587 (Pt 10): 2179-85. [PMID:19015189]

* Soleimani M. (2013) SLC26 Cl-/HCO3- exchangers in the kidney: roles in health and disease. Kidney Int, 84 (4): 657-66. [PMID:23636174]