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Notch receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Aberrant Notch signalling is implicated in a number of human cancers [7,12,14,17], and there is intense pharmaceutical activity being directed towards achieving clinically effective Notch pathway inhibition [3,10].

Targets

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notch receptor 1 C Show summary » More detailed page go icon to follow link

notch receptor 2 C Show summary » More detailed page go icon to follow link

notch receptor 3 C Show summary » More detailed page go icon to follow link

notch receptor 4 C Show summary »

Further reading

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References

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation (select format):

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 178 Suppl 1:S1-S26.