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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 1 | 2471 | 1p12 | NOTCH2 | notch receptor 2 | |
Mouse | 1 | 2473 | 3 42.42 cM | Notch2 | notch 2 | |
Rat | 1 | 2471 | 2q34 | Notch2 | notch receptor 2 |
Previous and Unofficial Names ![]() |
notch 2 | "Notch homolog 2 (Drosophila) |
Database Links ![]() |
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Alphafold | Q04721 (Hs), O35516 (Mm), Q9QW30 (Rn) |
CATH/Gene3D | 1.25.40.20 |
ChEMBL Target | CHEMBL3407320 (Hs) |
Ensembl Gene | ENSG00000134250 (Hs), ENSMUSG00000027878 (Mm), ENSRNOG00000018835 (Rn) |
Entrez Gene | 4853 (Hs), 18129 (Mm), 29492 (Rn) |
Human Protein Atlas | ENSG00000134250 (Hs) |
KEGG Gene | hsa:4853 (Hs), mmu:18129 (Mm), rno:29492 (Rn) |
OMIM | 600275 (Hs) |
Pharos | Q04721 (Hs) |
RefSeq Nucleotide | NM_024408 (Hs), NM_010928 (Mm), NM_024358 (Rn) |
RefSeq Protein | NP_077719 (Hs), NP_035058 (Mm), NP_077334 (Rn) |
UniProtKB | Q04721 (Hs), O35516 (Mm), Q9QW30 (Rn) |
Wikipedia | NOTCH2 (Hs) |
Download all structure-activity data for this target as a CSV file
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Key to terms and symbols | Click column headers to sort | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Immuno Process Associations | |||||||||||||||
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Clinically-Relevant Mutations and Pathophysiology ![]() |
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1. Gurney AL, Hoey TC, van der Horst ETH, Sato AK, Liu YC, Bruhns MF, Lewicki JA. (2012) Antibodies to notch receptors. Patent number: US8226943 B2. Assignee: Oncomed Pharmaceuticals, Inc.. Priority date: 08/07/2008. Publication date: 24/07/2012.