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2.3.2.- Aminoacyltransferases


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Aminoacyltransferases are ezymes that catalyse the transfer of an aminoacyl group from donor to acceptor, forming an ester or amide bond. There are 23 sub-families of aminoacyltransferase enzymes including peptidyl transferases, leucyltransferases, transglutaminases, and several families of ubiquitin-conjugating and transferases.


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Human RING-type E3 ubiquitin transferases (also known as ubiquitin ligases) include several groupings based on structure and function, of which 70 are tripartite motif (TRIM)-containing proteins. Whilst these 70 share conserved structural domains, they mediate diverse cellular functions.

How to cite this family page

Database page citation:

2.3.2.- Aminoacyltransferases. Accessed on 17/06/2024. IUPHAR/BPS Guide to PHARMACOLOGY,

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2019) The Concise Guide to PHARMACOLOGY 2019/20: Enzymes. Br J Pharmacol. 176 Issue S1: S297-S396.