Signal regulatory proteins

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Signal regulatory proteins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Signal-regulatory proteins (SIRP) are membrane proteins that are mainly expressed by myeloid cells. SIPRs play essential roles in immune cell and immune response regulation, whilst minimising damage to self [1].

Targets

SIRPA (CD172a) Show summary »« Hide summary More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

Signal regulatory proteins. Accessed on 06/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=989.

Concise Guide to PHARMACOLOGY citation:

Alexander SP, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets. Br J Pharmacol. 178 Suppl 1:S1-S26.