ChEMBL ligand: CHEMBL4297423 (Bet inhibitor ro6870810, BET INHIBITOR TEN-010, Jq-35, (s)-, Rg 6146, Ro-6870810, Ro6870810, RO6870810, (S)-JQ35)
bromodomain containing 4/Bromodomain-containing protein 4 in Human [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
bromodomain containing 4/Bromodomain-containing protein 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885]
ChEMBL	Alpha-assay: The binding activity of lead compounds with the BRD4 site 1 was determined by Alpha-assay with a 12-point dose response curve	B	7.61	pIC50	24.3	nM	IC50	US-10925881-B2. Treatment of conditions associated with hyperinsulinaemia (2021)
ChEMBL	Alpha-assay: The binding activity of lead compounds with the BRD4 site 2 was determined by Alpha-assay with a 12-point dose response curve	B	8.21	pIC50	6.13	nM	IC50	US-10925881-B2. Treatment of conditions associated with hyperinsulinaemia (2021)

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]