Synonyms: Antibiotic 273 A | U-70,138 | U-70138F
Compound class:
Synthetic organic
Comment: Paldimycin is a mixture of Paldimycins A (CAS 94555-00-7; CID 139597408) and B (CAS 94555-01-8; CID 139597428) which are also known as U-67963 and U-67964 which were derived from paulomycins A and B. It acts as a protein synthesis inhibitor. Paldimycin exhibited good antibacterial activity against Gram-positiive pathogens [2-3].
|
|
References |
1. Chandrasekar PH, Sluchak JA. (1989)
Susceptibility of staphylococci to paldimycin, and emergence of resistance, in vitro. J Antimicrob Chemother, 24 (5): 821-4. [PMID:2600003] |
2. Pfaller MA, Bale M, Barrett M. (1987)
In-vitro activity of paldimycin against methicillin-resistant and susceptible isolates of Staphylococcus aureus and S. epidermidis. J Antimicrob Chemother, 20 (2): 286-8. [PMID:3667485] |
3. Pohlod DJ, Saravolatz LD, Somerville MM. (1987)
In vitro susceptibility of gram-positive cocci to paldimycin. Antimicrob Agents Chemother, 31 (1): 104-7. [PMID:3105438] |