Synonyms: PZ-601 | SM-216601 | SMP-601
Compound class:
Synthetic organic
Comment: Razupenem is a penem class antibacterial. It inhibits cell wall synthesis, and is active against Gram-negative and Gram-positive bacteria [1-3].
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References |
1. Clark C, Kosowska-Shick K, McGhee P, Dewasse B, Beachel L, Appelbaum PC. (2009)
Resistance selection studies comparing the activity of razupenem (PTZ601) to vancomycin and linezolid against eight methicillin-resistant and two methicillin-susceptible Staphylococcus aureus strains. Antimicrob Agents Chemother, 53 (7): 3118-21. [PMID:19433566] |
2. El-Gamal MI, Brahim I, Hisham N, Aladdin R, Mohammed H, Bahaaeldin A. (2017)
Recent updates of carbapenem antibiotics. Eur J Med Chem, 131: 185-195. [PMID:28324783] |
3. Tran CM, Tanaka K, Yamagishi Y, Goto T, Mikamo H, Watanabe K. (2011)
In vitro antimicrobial activity of razupenem (SMP-601, PTZ601) against anaerobic bacteria. Antimicrob Agents Chemother, 55 (5): 2398-402. [PMID:21343447] |