Compound class:
Synthetic organic
Comment: DK-507k is a fluoroquinolone antibacterial. Compared to earlier generation fluoroquinolones it has improved activity against Gram-positive bacteria, including strains resistant to available quinolones [1]. DK-507k was being investigated as a potential treatment for community-acquired infections, but development has been discontinued following an analysis of Phase I trial data.
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References |
1. Otani T, Tanaka M, Ito E, Kurosaka Y, Murakami Y, Onodera K, Akasaka T, Sato K. (2003)
In vitro and in vivo antibacterial activities of DK-507k, a novel fluoroquinolone. Antimicrob Agents Chemother, 47 (12): 3750-9. [PMID:14638477] |