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Synonyms: 3,3',4',5,5',7-hexahydroxyflavone | cannabiscetin
Compound class:
Natural product
Comment: Myricetin is a plant-derived natural product. It is a flavonoid with a range of pharmacological activities that suggest potential therapeutic opportunities in diabetes, liver disease and cancer [2-3,5-7].
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Androutsopoulos VP, Papakyriakou A, Vourloumis D, Spandidos DA. (2011)
Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids. Bioorg Med Chem, 19 (9): 2842-9. [PMID:21482471] |
2. Babotă M, Frumuzachi O, Tanase C, Mocan A. (2024)
Efficacy of Myricetin Supplementation on Glucose and Lipid Metabolism: A Systematic Review and Meta-Analysis of In Vivo Mice Studies. Nutrients, 16 (21). [PMID:39519561] |
3. Chen M, Zhang S, Huang X, Zhang D, Zhu D, Ouyang C, Li Y. (2025)
The protective effects and mechanism of myricetin in liver diseases (Review). Mol Med Rep, 31 (4). [PMID:39917997] |
4. Hagiwara M, Inoue S, Tanaka T, Nunoki K, Ito M, Hidaka H. (1988)
Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases. Biochem Pharmacol, 37 (15): 2987-92. [PMID:3164998] |
5. Oldoni TLC, da Silva C, Bicas TC, Ayres BRB, Zanchet ER, Marafon F, da Silva AP, Carpes ST, Bagatini MD, Ascari J et al.. (2025)
Antihyperglycemic activity and bioguided isolation of phenolic compounds with antioxidant and cytotoxic properties from Syzygium malaccense leaves. Fitoterapia, 181: 106357. [PMID:39732206] |
6. Pattanaik SK, Anil MP, Jena S, Rath D. (2024)
A Mechanism-based Perspective on the Use of Flavonoids in the Treatment of Diabetes and its Complications. Curr Diabetes Rev, [Epub ahead of print]. [PMID:39620338] |
7. Phosrithong N, Ungwitayatorn J. (2010)
Molecular docking study on anticancer activity of plant-derived natural products. Med Chem Res, 19: 817–835. DOI: 10.1007/s00044-009-9233-5 |
8. Williams LK, Li C, Withers SG, Brayer GD. (2012)
Order and disorder: differential structural impacts of myricetin and ethyl caffeate on human amylase, an antidiabetic target. J Med Chem, 55 (22): 10177-86. [PMID:23050660] |