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Synonyms: LY-3819469 | LY3819469
Compound class:
Nucleic acid
Comment: Lepodisiran (LY3819469) is an apolipoprotein A synthesis reducer. It is a GalNac-conjugated short interfering RNA (siRNA) that was designed to treat atherosclerotic cardiovascular disease in patients with elevated lipoprotein A [1-2].
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Classification ![]() |
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| Compound class | Nucleic acid |
| Compound subclass | siRNA |
| Target | apolipoprotein A |
International Nonproprietary Names ![]() |
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| INN number | INN |
| 13068 | lepodisiran |
Synonyms ![]() |
| LY-3819469 | LY3819469 |
Database Links ![]() |
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| CAS Registry No. | 2808361-18-2 (source: WHO INN record) |
| GtoPdb PubChem SID | 507750342 |
| Search PubMed clinical trials | lepodisiran |
| Search PubMed titles | lepodisiran |
| Search PubMed titles/abstracts | lepodisiran |