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OBT076   Click here for help

GtoPdb Ligand ID: 13819

Synonyms: MEN-1309 | MEN1309 | OBT-076
Compound class: Synthetic organic
Comment: OBT076 is an antibody-drug conjugate (ADC) that comprises a fully human IgG1 anti-CD205 antibody conjugated by a cleavable linker to the cytotoxic maytansinoid microtubule disruptor DM4 [2]. It was designed for anti-tumour potential in solid and liquid cancers [1,3]DM4.
No information available.
Summary of Clinical Use Click here for help
OBT076 is an investigational stage oncology agent.
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT04064359 Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors Phase 1 Interventional Oxford BioTherapeutics Ltd
NCT05930951 Study of OBT076 Associated or Not in Patients with Recurrent or Metastatic Adenoid Cystic Carcinoma of the Head and Neck Phase 1 Interventional Groupe Oncologie Radiotherapie Tete et Cou