suvemcitug

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Compound class: Antibody

Comment: Suvemcitug (BD0801) is a humanized anti-VEGFA monoclonal antibody taht was desih=gned for anti-tumour action [1].

Bioactivity Comments
Binds to VEGFA₁₆₅ with affinity (Kd) of 0.012 nM and to VEGFA₁₆₄ with similar affinity [1]. In contrast bevacizumab does not bind to VEGFA₁₆₄.

Bioactivity Comments

Binds to VEGFA₁₆₅ with affinity (Kd) of 0.012 nM and to VEGFA₁₆₄ with similar affinity [1]. In contrast bevacizumab does not bind to VEGFA₁₆₄.

Selectivity at ligand targets

Key to terms and symbols

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Target			Sp.	Type	Action	Value	Parameter	Concentration range (M)	Reference
VEGFA			Hs	Antibody	Binding	10.9	pK_d	-	1
⤷	pK_d 10.9 (K_d 1.2x10^-11 M) [1] Description: Affinity for VEGFA₁₆₅