Synonyms: SC68376
Compound class:
Synthetic organic
Comment: SC-68376 is a potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase [3].
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Bioactivity Comments |
SC-68376 has been shown to inhibit immunoprecipitated p38 MAPK activity with an IC50 value between 2 and 5 μM [3]. This data is for a p38 MAPK isozyme mixture prepared from mesangial cell extracts. We have been unable to find publicly available isozyme specific inhibition data. |