crisantaspase

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crisantaspase

GtoPdb Ligand ID: 7347

Synonyms: asparaginase | Elspar® | Enrylaze® | L-asparaginase | L-asparagine amidohydrolase

crisantaspase is an approved drug (FDA (no history prior to 2011), EMA (2023))

Comment: Crisantaspase is a chemotherapy agent. The asparaginase enzyme can be isolated from Erwinia chrysanthemi or Escherichia coli. The two forms have different immunogenicity profiles. The amino acid sequence shown here is for the Erwina isoform, crisantaspase.

Summary
Biological activity
Clinical data
References
Structure

Bioactivity Comments
The substrate for this enzyme is L-asparagine, which it converts to aspartic acid and ammonia. We have not tagged a primary target for this enzyme drug.

Bioactivity Comments

The substrate for this enzyme is L-asparagine, which it converts to aspartic acid and ammonia. We have not tagged a primary target for this enzyme drug.