GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

glucarpidase   Click here for help

GtoPdb Ligand ID: 7450

Synonyms: Voraxaze®
Approved drug
glucarpidase is an approved drug (FDA (2012), EMA (2022))
Compound class: Peptide
Comment: Glucarpidase, a recombinant form of the bacterial enzyme carboxypeptidase G2 (cpg2). Pseudomonas sp cpg2 has UniProt id P06621.
Bioactivity Comments
As this drug metabolises an exogenously introduced compound (methotrexate) it does not act at a classic human primary target.