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Synonyms: Krystexxa® | puricase
pegloticase is an approved drug (FDA (2010), EMA (2013))
Compound class:
Peptide
Comment: Pegloticase is a porcine-like recombinant uricase, which is PEGylated to increase its biological half-life. The peptide sequence for the enzyme monomer is available in the ChEMBL entry. The enzyme is a tetramer, and lysine residues are PEGylated.
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| Bioactivity Comments |
| We have not tagged a primary drug target in this case, as the enzyme substrate is not a classical biological drug target. |
