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pegloticase   Click here for help

GtoPdb Ligand ID: 7463

Synonyms: Krystexxa® | puricase
Approved drug
pegloticase is an approved drug (FDA (2010), EMA (2013))
Compound class: Peptide
Comment: Pegloticase is a porcine-like recombinant uricase, which is PEGylated to increase its biological half-life. The peptide sequence for the enzyme monomer is available in the ChEMBL entry. The enzyme is a tetramer, and lysine residues are PEGylated.
Classification Click here for help
Compound class Peptide
Approved drug? Yes. EU EMA (2013)  |  US FDA (2010)
International Nonproprietary Names Click here for help
INN number INN
8934 pegloticase
Synonyms Click here for help
Krystexxa® | puricase
Database Links Click here for help
ChEMBL Ligand CHEMBL1237025
GtoPdb PubChem SID 187051766
Search PubMed clinical trials pegloticase
Search PubMed titles pegloticase
Search PubMed titles/abstracts pegloticase
Wikipedia Pegloticase