Synonyms: CGP 13501 | CGP-13501
Compound class:
Synthetic organic
Comment: CGP13501 is a positive allosteric modulator of GABAB Class C GPCRs [1] which potentiates GABA-induced GTPγ[35S] binding, but displays no intrinsic agonist activity.
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References |
1. Urwyler S, Mosbacher J, Lingenhoehl K, Heid J, Hofstetter K, Froestl W, Bettler B, Kaupmann K. (2001)
Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol, 60 (5): 963-71. [PMID:11641424] |