Compound class:
Synthetic organic
Comment: Compound 14b is reported as an irreversible and selective inhibitor of protein arginine deiminase type III (PADI3) [1].
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References |
1. Jamali H, Khan HA, Stringer JR, Chowdhury S, Ellman JA. (2015)
Identification of multiple structurally distinct, nonpeptidic small molecule inhibitors of protein arginine deiminase 3 using a substrate-based fragment method. J Am Chem Soc, 137 (10): 3616-21. [PMID:25742366] |