Synonyms: SMP-114
Compound class:
Synthetic organic
Comment: Rimacalib (SMP-114) is an isoxazole derivative inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) [2], CAMKII being an established pharmacological target for chronic inflammatory pain [1], as well as being involved in modulating synaptic plasticity and learning and memory processes.
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
N'-[3-[(1S)-1-(3-fluoro-4-phenylphenyl)ethyl]-1,2-oxazol-5-yl]morpholine-4-carboximidamide |
International Nonproprietary Names | |
INN number | INN |
8597 | rimacalib |
Synonyms |
SMP-114 |
Database Links | |
CAS Registry No. | 215174-50-8 (source: PubChem) |
ChEMBL Ligand | CHEMBL2107772 |
GtoPdb PubChem SID | 328083466 |
PubChem CID | 9800765 |
Search Google for chemical match using the InChIKey | MYTIJGWONQOOLC-HNNXBMFYSA-N |
Search Google for chemicals with the same backbone | MYTIJGWONQOOLC |
Search PubMed clinical trials | rimacalib |
Search PubMed titles | rimacalib |
Search PubMed titles/abstracts | rimacalib |
UniChem Compound Search for chemical match using the InChIKey | MYTIJGWONQOOLC-HNNXBMFYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | MYTIJGWONQOOLC-HNNXBMFYSA-N |