Synonyms: BI-665915 | compound 69 [PMID: 25671290] [1]
Compound class:
Synthetic organic
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Immunopharmacology Comments |
FLAP inhibitors have therapeutic anti-inflammatory potential that is mediated via inhibition of the arachadonic acid to leukotriene biosynthetic pathway. Such inhibitors were developed as alternatives to the 5-LOX inhibitors (e.g. Zileuton) and CysLT1 antagonists (e.g. Montelukast) that also leukotriene production. |