Ligand id: 10117

Name: AUNP-12

Structure and Physico-chemical Properties

2D Structure
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View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
In preclinical models, AUNP-12 inhibited the growth of melanoma, breast tumours and lung metastases in vivo [3].
Selectivity at other protein targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
programmed cell death 1 (CD279) Hs Inhibitor Binding 9.1 pEC50 - 3
pEC50 9.1 (EC50 7.2x10-10 M) [3]
Description: Inhibition of soluble PD-1 binding to HEK293 cells stably expressing human PD-L2.