imdevimab   Click here for help

GtoPdb Ligand ID: 11328

Synonyms: REGN-10987 | REGN10987 | Ronapreve® (imdevimab + casirivimab)
Approved drug
imdevimab is an approved drug (Japan and UK MHRA (2021))
Compound class: Antibody
Comment: Imdevimab is a fully human monoclonal antibody against the surface spike protein of SARS-CoV-2 [1-2]. It is a virus neutralising mAb that was developed by Regeneron.
Click here for help
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CoV Spike glycoprotein SARS-CoV-2 Antibody Binding 9.6 pIC50 - 2
pIC50 9.6 (IC50 2.3x10-10 M) [2]
Description: IC50 for ability of mAb to compete with spike protein for binding to hACE2.