regdanvimab   Click here for help

GtoPdb Ligand ID: 11332

Synonyms: CT-P-59 | CT-P59 | Regkirona®
Approved drug
regdanvimab is an approved drug (South Korea & EMA (2021))
Compound class: Antibody
Comment: Regdanvimab (CT-P59) is a recombinant monoclonal antibody against the surface spike protein of SARS-CoV-2 [1]. It was developed by Celltrion. Regdanvimab inhibits SARS-CoV-2 infection via steric hindrance of its binding to human ACE2.
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Selectivity at other protein targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CoV Spike glycoprotein SARS-CoV-2 Antibody Binding 10.6 pKd - 1
pKd 10.6 (Kd 2.7x10-11 M) [1]
Description: Binding affinity to SARS-CoV-2 RBD measured in a surface plasmon resonance assay.