UDP-galactose

Ligand id: 1782

Name: UDP-galactose

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 9
Rotatable bonds 9
Topological polar surface area 316.61
Molecular weight 566.06
XLogP -5.42
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
GPR17
P2Y14 receptor
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
UDP-galactose transporter 5,7
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
P2Y14 receptor Mm Agonist Full agonist 7.6 pEC50 - 3
pEC50 7.6 [3]
GPR17 Hs Agonist Agonist 6.0 – 8.9 pEC50 - 1-2
pEC50 6.0 – 8.9 (EC50 1.1x10-6 – 1.2x10-9 M) [1-2]
Description: [35S]GTPγS binding to 1321N1 cell membranes expressing hGPR17.
GPR17 Mm Agonist Agonist 7.2 pEC50 - 6
pEC50 7.2 (EC50 6.8x10-8 M) [6]
P2Y14 receptor Rn Agonist Full agonist 7.1 pEC50 - 3
pEC50 7.1 [3]
P2Y14 receptor Hs Agonist Full agonist 7.0 pEC50 - 4
pEC50 7.0 [4]
Ligand mentioned in the following text fields