presqualene diphosphate

Ligand id: 3053

Name: presqualene diphosphate

Abbreviated name: Z-PSDP

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 18
Topological polar surface area 132.91
Molecular weight 586.32
XLogP 7.58
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Enzymes Catalysing Reactions with this Compound as a Substrate or Product
Enzyme EC number Reaction Reference
squalene synthase 2.5.1.21 2trans,trans-farnesyl diphosphate -> presqualene diphosphate + diphosphate
presqualene diphosphate + NAD(P)H + H+ -> squalene + diphosphate + NAD(P)+