Ligand id: 4222

Name: IP3

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 15
Hydrogen bond donors 9
Rotatable bonds 6
Topological polar surface area 290.4
Molecular weight 419.96
XLogP -7.29
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
IP3R1 Hs Activator - - - -
endogenous; nM - μM range
IP3R2 Hs Activator - - - -
endogenous; nM - μM range
IP3R3 Hs Activator - - - -
endogenous; nM - μM range
Ligand mentioned in the following text fields