IP3

Ligand id: 4222

Name: IP3

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 15
Hydrogen bond donors 9
Rotatable bonds 6
Topological polar surface area 290.4
Molecular weight 419.96
XLogP -7.29
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
IP3R1
IP3R2
IP3R3
Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
IP3R1 Hs Activator - - - -
endogenous; nM - μM range
IP3R2 Hs Activator - - - -
endogenous; nM - μM range
IP3R3 Hs Activator - - - -
endogenous; nM - μM range
Ligand mentioned in the following text fields