5,6-epoxyeicosatrienoic acid

Ligand id: 6304

Name: 5,6-epoxyeicosatrienoic acid

Abbreviated name: 5,6-EET

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 14
Topological polar surface area 49.83
Molecular weight 320.24
XLogP 6.58
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
TRPV4 Mm Activator Agonist 6.9 pEC50 - 1
pEC50 6.9 [1]
Voltage: -60.0 mV
Ligand mentioned in the following text fields