[des-Arg9]bradykinin   

GtoPdb Ligand ID: 646

Synonyms: [des-Arg9]BK
Species: Human, Mouse, Rat
2D Structure
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SMILES / InChI / InChIKey
Canonical SMILES OCC(C(=O)N1CCCC1C(=O)NC(C(=O)O)Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCCN=C(N)N)N
Isomeric SMILES OCC(C(=O)N1CCCC1C(=O)NC(C(=O)O)Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCCN=C(N)N)N
InChI InChI=1S/C44H61N11O10/c45-29(15-7-19-48-44(46)47)40(61)55-22-10-18-35(55)42(63)54-21-8-16-33(54)38(59)49-25-36(57)50-30(23-27-11-3-1-4-12-27)37(58)52-32(26-56)41(62)53-20-9-17-34(53)39(60)51-31(43(64)65)24-28-13-5-2-6-14-28/h1-6,11-14,29-35,56H,7-10,15-26,45H2,(H,49,59)(H,50,57)(H,51,60)(H,52,58)(H,64,65)(H4,46,47,48)
InChI Key VCEHWDBVPZFHAG-UHFFFAOYSA-N
Natural/Endogenous Targets
Target
B1 receptor
B2 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
B1 receptor Mm Agonist Full agonist 9.2 pKi - 3
pKi 9.2 [3]
B1 receptor Hs Agonist Full agonist 5.7 – 5.8 pKi - 1,4
pKi 5.7 – 5.8 [1,4]
B2 receptor Mm Agonist Full agonist 5.2 pIC50 - 2
pIC50 5.2 [2]
B2 receptor Hs Agonist Full agonist 5.1 pIC50 - 2
pIC50 5.1 [2]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields