ofatumumab   Click here for help

GtoPdb Ligand ID: 6778

Synonyms: Arzerra® | GSK 1841157 | GSK1841157 | humax-CD20 | Kesimpta® (subcutaneous) | OMB-157 | OMB157
Approved drug Immunopharmacology Ligand
ofatumumab is an approved drug (FDA (2009), EMA (2010))
Compound class: Antibody
Comment: Ofatumumab is a type I anti-CD20 monoclonal, designed to target surface CD20 on B-lymphocytes.
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Selectivity at other protein targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD20 (membrane-spanning 4-domains, subfamily A, member 1) Primary target of this compound Hs Antibody Binding 9.9 pKd - 1
pKd 9.9 (Kd 1.21x10-10 M) [1]
Description: Binding affinity for clone 2F2 ((HuMax-CD20).