View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments

The patents covering rituximab do not contain any data regarding antibody-antigen affinity [2-3], but a dissociation constant is provided by Stein et al (2004) [6].

Selectivity at other protein targets
Key to terms and symbols		Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference CD20 (membrane-spanning 4-domains, subfamily A, member 1) Hs Antibody Binding 8.5 pKd - 6 ⤷ pKd 8.5 (Kd 3.1x10-9 M) [6]