girentuximab

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girentuximab

GtoPdb Ligand ID: 7987

Synonyms: cG250 | G250 | Rencarex® (proposed proprietary name) | WX-G250

Comment: Girentuximab is a monoclonal antibody directed against carbonic anhydrase 9 (CA9) [5].
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record.

Summary
Biological activity
Clinical data
References

Bioactivity Comments
We have been unable to find affinity data for the interaction between girentuximab and CA9. Primary target identity is confirmed in a report by Zatovicova et al (2014) [5] which identifies the antigenic site for antibody binding to CA9 as well as the mechanisms regulating internalisation and recycling of the antibody.

Bioactivity Comments

We have been unable to find affinity data for the interaction between girentuximab and CA9. Primary target identity is confirmed in a report by Zatovicova et al (2014) [5] which identifies the antigenic site for antibody binding to CA9 as well as the mechanisms regulating internalisation and recycling of the antibody.