elgemtumab   Click here for help

GtoPdb Ligand ID: 8715

Synonyms: LJM716 | NVS201010
Compound class: Antibody
Comment: Elgemtumab is a fully human anti-ERBB3 (HER3) investigational monoclonal antibody, with antineoplastic potential.
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record.
Protein BLAST alignment reveals that 100% matched peptide sequences for elgemtumab are contained in patent US8735551 B2 [1].
Click here for help
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
erb-b2 receptor tyrosine kinase 3 Primary target of this compound Hs Antibody Binding 10.6 – 11.4 pKd - 1
pKd 10.6 – 11.4 (Kd 2.6x10-11 – 4x10-12 M) [1]