Ligand id: 8717

Name: evinacumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
The affinity value in the table below represents antibody binding to full length human ANGPTL3. The corresponding Kd value for binding to the N-terminal coiled-coil domain of ANGPTL3 is reported as 0.66nM [3].
Selectivity at ligand targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
angiopoietin-like 3 Hs Antibody Binding 8.9 pKd - 3
pKd 8.9 (Kd 1.35x10-9 M) [3]