Ligand id: 8717

Name: evinacumab

Bioactivity Comments
The affinity value in the table below represents antibody binding to full length human ANGPTL3. The corresponding Kd value for binding to the N-terminal coiled-coil domain of ANGPTL3 is reported as 0.66nM [3].
Selectivity at ligand targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
angiopoietin-like 3 Hs Antibody Binding 8.9 pKd - 3
pKd 8.9 (Kd 1.35x10-9 M) [3]