Ligand id: 8719

Name: isatuximab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
The affinity values in the table below represents the Kds provided in US20110262454 A1 [2] for a range of tested CD38-binding antibodies. The Kd for hu38SB19 is 0.23 nM [2].
Selectivity at other protein targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD38 Hs Antibody Binding 8.5 – 10.0 pKd - 2
pKd 8.5 – 10.0 (Kd 3x10-9 – 1x10-10 M) [2]